Enhancement of Thiamin Content inArabidopsis thalianaby Metabolic Engineering
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چکیده
منابع مشابه
Enhancement of folates in plants through metabolic engineering.
Humans depend on plants as a major source of dietary folates. Inadequate dietary levels of the vitamin folate can lead to megaloblastic anemia, birth defects, impaired cognitive development, and increased risk of cardiovascular disease and cancer. The biofortification of folate levels in food crops is a target for metabolic engineering. Folates are synthesized de novo from pterins and para-amin...
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Potato tuber is a high yielding food crop known for its high levels of starch accumulation but only negligible levels of triacylglycerol (TAG). In this study, we evaluated the potential for lipid production in potato tubers by simultaneously introducing three transgenes, including WRINKLED 1 (WRI1), DIACYLGLYCEROL ACYLTRANSFERASE 1 (DGAT1) and OLEOSIN under the transcriptional control of tuber-...
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A genetic screen was developed for the identification of genes related to thiamin biosynthesis and degradation. Genes conferring resistance to bacimethrin or 4-amino-2-trifluoromethyl-5-hydroxymethylpyrimidine were selected from Escherichia coli and Bacillus subtilis genomic libraries. Hits from the selection included the known thiamin biosynthetic genes thiC, thiE, and dxs as well as five gene...
متن کاملMetabolic engineering.
Metabolic engineering is the science that combines systematic analysis of metabolic and other pathways with molecular biological techniques to improve cellular properties by designing and implementing rational genetic modifications. As such, metabolic engineering deals with the measurement of metabolic fluxes and elucidation of their control as determinants of metabolic function and cell physio...
متن کاملMetabolic engineering
MetaCyc database http://metacyc.org/ MetaCyc is a database of metabolic pathways containing more than 1400 pathways from more than 1800 organisms. KEGG pathway database http://www.genome.jp/kegg/pathway.html The KEGG pathway database consists of a collection of manually-curated metabolic maps with connections to metabolite, enzyme and organismal data. KEGG also contains tools for reconstructing...
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ژورنال
عنوان ژورنال: Plant and Cell Physiology
سال: 2015
ISSN: 0032-0781,1471-9053
DOI: 10.1093/pcp/pcv148